Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 18 Researches
6.6
USERS' SCORE
Good
Based on 22 Reviews
8.6
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%*
Echinacea Extract Blend
100 mg
†
Echinacea purpurea root supercritical CO2 extract, Echinacea angustifolia root supercritical CO2 extract
Alkylamides
9 mg
†
Proprietary Extract Blend
800 mg
†
Andrographis (Andrographis paniculata) aerial parts extract, Organic Black Elderberry (Sambucus nigra) fruit extract, Organic Ginger (Zingiber officinale) root supercritical CO2 extract
Top Medical Research Studies
9
In a comprehensive clinical trial, we examined the effectiveness of Echinacea purpurea as a preventative measure against the common cold. This research stands out as the largest of its kind, evaluating both the safety and benefits of Echinacea over a long-term treatment period of four months.
We found that this proprietary extract of Echinacea, known as Echinaforce, proved to be beneficial in several ways. It significantly reduced the total number of cold episodes and the duration of those colds. Additionally, participants required fewer medications to cope with their symptoms, highlighting Echinacea's potential as a natural remedy.
Importantly, the extract showed impressive results, particularly for individuals who often experience recurrent infections. The study also indicated that the more closely individuals followed the recommended protocol, the better the preventive effects. Overall, we feel encouraged by the positive risk-to-benefit ratio of Echinacea purpurea when taken as directed for the common cold.
We found that this proprietary extract of Echinacea, known as Echinaforce, proved to be beneficial in several ways. It significantly reduced the total number of cold episodes and the duration of those colds. Additionally, participants required fewer medications to cope with their symptoms, highlighting Echinacea's potential as a natural remedy.
Importantly, the extract showed impressive results, particularly for individuals who often experience recurrent infections. The study also indicated that the more closely individuals followed the recommended protocol, the better the preventive effects. Overall, we feel encouraged by the positive risk-to-benefit ratio of Echinacea purpurea when taken as directed for the common cold.
Read More
9
Echinaforce® shows promise for colds
We explored how Echinaforce®, a standardized extract from the Echinacea purpurea plant, can affect respiratory tract infections, including the common cold. In recent research, this treatment was subjected to a rigorous examination through a randomized, double-blind, placebo-controlled study lasting four months. This methodology is important because it allows for a clear comparison between those receiving the treatment and those receiving a placebo.
During the study, we observed that Echinaforce® exhibits immunomodulatory and broad antiviral effects against various respiratory viruses. Notably, it blocks proteins like Haemagglutinin and Neuraminidase, which are often involved in viral replication. One of the significant advantages of Echinaforce® over traditional antiviral medications, such as Oseltamivir, is that it does not lead to viral resistance.
The findings support the idea that Echinaforce® can enhance immune resistance and offers both long-term and short-term benefits for preventing and treating common cold symptoms. This makes it a promising option for individuals looking for natural ways to boost their immune system and combat viral infections.
During the study, we observed that Echinaforce® exhibits immunomodulatory and broad antiviral effects against various respiratory viruses. Notably, it blocks proteins like Haemagglutinin and Neuraminidase, which are often involved in viral replication. One of the significant advantages of Echinaforce® over traditional antiviral medications, such as Oseltamivir, is that it does not lead to viral resistance.
The findings support the idea that Echinaforce® can enhance immune resistance and offers both long-term and short-term benefits for preventing and treating common cold symptoms. This makes it a promising option for individuals looking for natural ways to boost their immune system and combat viral infections.
Read More
8
We conducted a study to explore the safety and effectiveness of Echinacea purpurea in preventing common cold episodes among 755 healthy participants over four months. Participants were randomly assigned to receive either an extract of Echinacea or a placebo, and they diligently recorded any adverse events or cold-related issues in diaries throughout the study period.
Our findings revealed that Echinacea appears to support cold prevention by reducing the number of cold episodes and the overall days spent unwell. Those who used Echinacea experienced fewer occasions requiring pain relief medications and showed a significant decrease in illness due to virally confirmed colds, especially those caused by enveloped viruses. Notably, participants who followed the treatment protocol closely benefitted the most, showing enhanced preventive effects from Echinacea.
Throughout the study, safety was carefully monitored, revealing that the incidence of adverse events was similar between those taking Echinacea and those on placebo. This indicates that Echinacea has a favorable safety profile comparable to taking no active treatment at all.
Overall, regular intake of Echinacea purpurea can offer a valuable boost in our defenses against the common cold, making it a potential natural remedy for those looking to reduce the frequency and severity of colds.
Our findings revealed that Echinacea appears to support cold prevention by reducing the number of cold episodes and the overall days spent unwell. Those who used Echinacea experienced fewer occasions requiring pain relief medications and showed a significant decrease in illness due to virally confirmed colds, especially those caused by enveloped viruses. Notably, participants who followed the treatment protocol closely benefitted the most, showing enhanced preventive effects from Echinacea.
Throughout the study, safety was carefully monitored, revealing that the incidence of adverse events was similar between those taking Echinacea and those on placebo. This indicates that Echinacea has a favorable safety profile comparable to taking no active treatment at all.
Overall, regular intake of Echinacea purpurea can offer a valuable boost in our defenses against the common cold, making it a potential natural remedy for those looking to reduce the frequency and severity of colds.
Read More
Most Useful Reviews
10
Highly effective remedy
5 people found this helpful
Effective cold medicine! A really effective remedy. At the first signs of the common cold, I followed the suggested regimen. I managed not to get ill, and after three days, all symptoms vanished as if by magic. I initially bought one jar for a trial, but I’ve now ordered two more. In St. Petersburg, it’s an essential item during off-season! I highly recommend it.
Read More
10
My golden ticket
3 people found this helpful
The best line of defence! As a Canadian, I can't find Gaia in Canada. While in California, I caught a sore throat and bought these at a health food store. I took them enthusiastically—10 a day at onset—and they worked brilliantly. I've been having them shipped ever since, especially with flu season approaching, along with Allimax at the first signs of a common cold; it's my golden ticket!
Read More
9
Stronger than alternatives
3 people found this helpful
Quick Defence works! I recently tried Gaia Herbs Quick Defence with fantastic results. After taking it for two days (40 caps) to address strong viral symptoms resembling a cold/flu, I felt fine on the third day. Previously, I used Gaia Herbs echinacea, but Quick Defence proved more effective, and the dosing was straightforward. I will keep it handy.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 18 Researches
6.6
- All Researches
9
We're diving into the effectiveness of Echinacea for children dealing with acute cold and flu symptoms. A total of 79 children, aged between 4 and 12, were included in this study. We randomized them to receive either three or five doses of Echinaforce Junior tablets daily, allowing us to compare the benefits of 1200 mg versus 2000 mg of Echinacea extract.
During the cold episodes, parents diligently recorded their child's respiratory symptoms, while both parents and physicians provided feedback on how well the treatment was tolerated. Our observations revealed that Echinacea was well-received, boasting an impressive tolerability rate of over 96%. On average, cold episodes lasted 7.5 days, and most children fully recovered within 10 days.
Notably, we found that those taking five doses of Echinacea daily experienced a shorter average duration of symptoms, cutting the episode time by about 1.7 days compared to those taking three doses. This effective symptom relief led to low antibiotic prescriptions, with only 4.6% of children needing them. Overall, we see Echinacea tablets as a promising option for managing acute cold episodes in children, especially at higher doses.
During the cold episodes, parents diligently recorded their child's respiratory symptoms, while both parents and physicians provided feedback on how well the treatment was tolerated. Our observations revealed that Echinacea was well-received, boasting an impressive tolerability rate of over 96%. On average, cold episodes lasted 7.5 days, and most children fully recovered within 10 days.
Notably, we found that those taking five doses of Echinacea daily experienced a shorter average duration of symptoms, cutting the episode time by about 1.7 days compared to those taking three doses. This effective symptom relief led to low antibiotic prescriptions, with only 4.6% of children needing them. Overall, we see Echinacea tablets as a promising option for managing acute cold episodes in children, especially at higher doses.
Read More
9
In a comprehensive clinical trial, we examined the effectiveness of Echinacea purpurea as a preventative measure against the common cold. This research stands out as the largest of its kind, evaluating both the safety and benefits of Echinacea over a long-term treatment period of four months.
We found that this proprietary extract of Echinacea, known as Echinaforce, proved to be beneficial in several ways. It significantly reduced the total number of cold episodes and the duration of those colds. Additionally, participants required fewer medications to cope with their symptoms, highlighting Echinacea's potential as a natural remedy.
Importantly, the extract showed impressive results, particularly for individuals who often experience recurrent infections. The study also indicated that the more closely individuals followed the recommended protocol, the better the preventive effects. Overall, we feel encouraged by the positive risk-to-benefit ratio of Echinacea purpurea when taken as directed for the common cold.
We found that this proprietary extract of Echinacea, known as Echinaforce, proved to be beneficial in several ways. It significantly reduced the total number of cold episodes and the duration of those colds. Additionally, participants required fewer medications to cope with their symptoms, highlighting Echinacea's potential as a natural remedy.
Importantly, the extract showed impressive results, particularly for individuals who often experience recurrent infections. The study also indicated that the more closely individuals followed the recommended protocol, the better the preventive effects. Overall, we feel encouraged by the positive risk-to-benefit ratio of Echinacea purpurea when taken as directed for the common cold.
Read More
9
Echinaforce® shows promise for colds
We explored how Echinaforce®, a standardized extract from the Echinacea purpurea plant, can affect respiratory tract infections, including the common cold. In recent research, this treatment was subjected to a rigorous examination through a randomized, double-blind, placebo-controlled study lasting four months. This methodology is important because it allows for a clear comparison between those receiving the treatment and those receiving a placebo.
During the study, we observed that Echinaforce® exhibits immunomodulatory and broad antiviral effects against various respiratory viruses. Notably, it blocks proteins like Haemagglutinin and Neuraminidase, which are often involved in viral replication. One of the significant advantages of Echinaforce® over traditional antiviral medications, such as Oseltamivir, is that it does not lead to viral resistance.
The findings support the idea that Echinaforce® can enhance immune resistance and offers both long-term and short-term benefits for preventing and treating common cold symptoms. This makes it a promising option for individuals looking for natural ways to boost their immune system and combat viral infections.
During the study, we observed that Echinaforce® exhibits immunomodulatory and broad antiviral effects against various respiratory viruses. Notably, it blocks proteins like Haemagglutinin and Neuraminidase, which are often involved in viral replication. One of the significant advantages of Echinaforce® over traditional antiviral medications, such as Oseltamivir, is that it does not lead to viral resistance.
The findings support the idea that Echinaforce® can enhance immune resistance and offers both long-term and short-term benefits for preventing and treating common cold symptoms. This makes it a promising option for individuals looking for natural ways to boost their immune system and combat viral infections.
Read More
9
In our study, we investigated the effectiveness of a multiherbal formula called Immumax, which includes Echinacea, alongside garlic, Nigella sativa oil, Panax ginseng, vitamin C, and zinc, in treating the common cold. Conducted in an outpatient setting, this double-blind, randomized, controlled trial involved 62 participants who exhibited common cold symptoms. They were divided into two groups; one received Immumax, while the other received a placebo.
Our findings revealed that the patients taking Immumax experienced a significant reduction in the duration and severity of their cold symptoms compared to those on the placebo. Specifically, the average time for symptoms to resolve was notably quicker—4 days for Immumax users versus 8 days for the placebo group. Additionally, by day four and eight, there was a significant decrease in overall symptom severity scores among Immumax recipients.
Overall, we can confidently say that the inclusion of Echinacea in the multiherbal formula contributes positively to managing cold symptoms, aiding in quicker recovery. However, it’s essential to note that we didn't isolate the individual effects of Echinacea, so while it seems beneficial within this combination, we can’t definitively attribute all the positive effects solely to Echinacea.
Our findings revealed that the patients taking Immumax experienced a significant reduction in the duration and severity of their cold symptoms compared to those on the placebo. Specifically, the average time for symptoms to resolve was notably quicker—4 days for Immumax users versus 8 days for the placebo group. Additionally, by day four and eight, there was a significant decrease in overall symptom severity scores among Immumax recipients.
Overall, we can confidently say that the inclusion of Echinacea in the multiherbal formula contributes positively to managing cold symptoms, aiding in quicker recovery. However, it’s essential to note that we didn't isolate the individual effects of Echinacea, so while it seems beneficial within this combination, we can’t definitively attribute all the positive effects solely to Echinacea.
Read More
9
We explored the effects of specific compounds called alkylamides, found in a medicinal herb, on common cold symptoms. Our study focused on the antiviral and inflammatory responses of these alkylamides, particularly how they interact with respiratory viruses like rhinovirus and influenza.
We found that one alkylamide, Dodeca-2,4-Dienoic acid isobutylamide, was particularly effective. It showed a strong ability to inhibit the replication of these viruses while also reducing the production of a specific cytokine called IL-8. High levels of IL-8 are linked to many cold symptoms and other respiratory infections.
The promising results, along with low toxicity, suggest that this alkylamide could be a useful treatment for those suffering from colds or flu. Overall, our findings highlight the potential benefits of alkylamides in alleviating cold symptoms and promoting better respiratory health.
We found that one alkylamide, Dodeca-2,4-Dienoic acid isobutylamide, was particularly effective. It showed a strong ability to inhibit the replication of these viruses while also reducing the production of a specific cytokine called IL-8. High levels of IL-8 are linked to many cold symptoms and other respiratory infections.
The promising results, along with low toxicity, suggest that this alkylamide could be a useful treatment for those suffering from colds or flu. Overall, our findings highlight the potential benefits of alkylamides in alleviating cold symptoms and promoting better respiratory health.
Read More
User Reviews
USERS' SCORE
Good
Based on 22 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
10
Highly effective remedy
5 people found this helpful
Effective cold medicine! A really effective remedy. At the first signs of the common cold, I followed the suggested regimen. I managed not to get ill, and after three days, all symptoms vanished as if by magic. I initially bought one jar for a trial, but I’ve now ordered two more. In St. Petersburg, it’s an essential item during off-season! I highly recommend it.
Read More
10
My golden ticket
3 people found this helpful
The best line of defence! As a Canadian, I can't find Gaia in Canada. While in California, I caught a sore throat and bought these at a health food store. I took them enthusiastically—10 a day at onset—and they worked brilliantly. I've been having them shipped ever since, especially with flu season approaching, along with Allimax at the first signs of a common cold; it's my golden ticket!
Read More
9
Stronger than alternatives
3 people found this helpful
Quick Defence works! I recently tried Gaia Herbs Quick Defence with fantastic results. After taking it for two days (40 caps) to address strong viral symptoms resembling a cold/flu, I felt fine on the third day. Previously, I used Gaia Herbs echinacea, but Quick Defence proved more effective, and the dosing was straightforward. I will keep it handy.
Read More
10
Wonders for symptoms
2 people found this helpful
This remedy is what I use as soon as I suspect I have cold symptoms. It works wonders! My first experience was waking up with a runny nose and sneezing, but after taking it as directed and drinking plenty of fluids, I woke up the next day symptom-free.
Read More
7.5
Effective for symptoms
2 people found this helpful
It helps with the first signs of a common cold. I ordered it in stock and found that sometimes taking capsules for just one day is sufficient for noticeable effects.
Read More
Frequently Asked Questions
10
Highly effective remedy
5 people found this helpful
Effective cold medicine! A really effective remedy. At the first signs of the common cold, I followed the suggested regimen. I managed not to get ill, and after three days, all symptoms vanished as if by magic. I initially bought one jar for a trial, but I’ve now ordered two more. In St. Petersburg, it’s an essential item during off-season! I highly recommend it.
9
Stronger than alternatives
3 people found this helpful
Quick Defence works! I recently tried Gaia Herbs Quick Defence with fantastic results. After taking it for two days (40 caps) to address strong viral symptoms resembling a cold/flu, I felt fine on the third day. Previously, I used Gaia Herbs echinacea, but Quick Defence proved more effective, and the dosing was straightforward. I will keep it handy.
7.5
Effective for symptoms
2 people found this helpful
It helps with the first signs of a common cold. I ordered it in stock and found that sometimes taking capsules for just one day is sufficient for noticeable effects.
10
Wonders for symptoms
2 people found this helpful
This remedy is what I use as soon as I suspect I have cold symptoms. It works wonders! My first experience was waking up with a runny nose and sneezing, but after taking it as directed and drinking plenty of fluids, I woke up the next day symptom-free.
10
My golden ticket
3 people found this helpful
The best line of defence! As a Canadian, I can't find Gaia in Canada. While in California, I caught a sore throat and bought these at a health food store. I took them enthusiastically—10 a day at onset—and they worked brilliantly. I've been having them shipped ever since, especially with flu season approaching, along with Allimax at the first signs of a common cold; it's my golden ticket!
8
Arrests cold progress
1 people found this helpful
Recommended for emergencies. This must be taken at the first signs of a cough or cold, adhering closely to the dosage. It helped halt the progression of the illness, so I recovered rapidly. It's also good to take additional measures like liposomal vitamin C and quality honey. The capsule size is manageable.
9
Prevents cold onset
I always have Quick Defense on hand. It seems beneficial; when I sense a cold coming on, I take it, and the cold usually doesn't develop.
9
Speeds recovery
Convinced. My husband swears by this product. He is prone to head colds and feels it helps him recover quickly.
9
Quick illness support
An effective remedy for strengthening the immune system during colds. The capsules are fast-acting, especially at the first signs of illness. I appreciate that the product is natural and easy to use, although the packaging is only sufficient for a brief course.
We explored the effects of Echinacea purpurea, a popular herbal remedy, on our immune response to the common cold. The study employed advanced techniques to measure how a standardized extract of Echinacea affects THP-1 monocytes, a type of immune cell. Through transcriptome, epigenome, and kinome profiling, we identified significant immunomodulatory effects from the Echinacea treatment.
Our findings revealed that Echinacea stimulates antiviral pathways responsible for activating immune responses. This includes enhancing signaling from interferons, which act as messengers in our immune system, and boosting the activity of pattern recognition receptors, which help identify pathogens. We also observed changes in genes related to inflammation and the body's metabolic processes, indicating a comprehensive strengthening of our innate immunity.
Furthermore, Echinacea treatment was linked to increased DNA methylation at specific genomic sites. This may inhibit the expression of endogenous retroviral sequences, contributing to a protective evolutionary response to viral infections. Such changes suggest that Echinacea may not only help alleviate symptoms but could also reduce the duration of colds caused by various coronaviruses, including new variants like SARS-CoV-2.
Overall, we believe Echinacea purpurea shows promise as a supportive treatment for common colds, particularly in boosting our inherent antiviral defenses during infections.
Our findings revealed that Echinacea stimulates antiviral pathways responsible for activating immune responses. This includes enhancing signaling from interferons, which act as messengers in our immune system, and boosting the activity of pattern recognition receptors, which help identify pathogens. We also observed changes in genes related to inflammation and the body's metabolic processes, indicating a comprehensive strengthening of our innate immunity.
Furthermore, Echinacea treatment was linked to increased DNA methylation at specific genomic sites. This may inhibit the expression of endogenous retroviral sequences, contributing to a protective evolutionary response to viral infections. Such changes suggest that Echinacea may not only help alleviate symptoms but could also reduce the duration of colds caused by various coronaviruses, including new variants like SARS-CoV-2.
Overall, we believe Echinacea purpurea shows promise as a supportive treatment for common colds, particularly in boosting our inherent antiviral defenses during infections.
9
We're diving into the effectiveness of Echinacea for children dealing with acute cold and flu symptoms. A total of 79 children, aged between 4 and 12, were included in this study. We randomized them to receive either three or five doses of Echinaforce Junior tablets daily, allowing us to compare the benefits of 1200 mg versus 2000 mg of Echinacea extract.
During the cold episodes, parents diligently recorded their child's respiratory symptoms, while both parents and physicians provided feedback on how well the treatment was tolerated. Our observations revealed that Echinacea was well-received, boasting an impressive tolerability rate of over 96%. On average, cold episodes lasted 7.5 days, and most children fully recovered within 10 days.
Notably, we found that those taking five doses of Echinacea daily experienced a shorter average duration of symptoms, cutting the episode time by about 1.7 days compared to those taking three doses. This effective symptom relief led to low antibiotic prescriptions, with only 4.6% of children needing them. Overall, we see Echinacea tablets as a promising option for managing acute cold episodes in children, especially at higher doses.
During the cold episodes, parents diligently recorded their child's respiratory symptoms, while both parents and physicians provided feedback on how well the treatment was tolerated. Our observations revealed that Echinacea was well-received, boasting an impressive tolerability rate of over 96%. On average, cold episodes lasted 7.5 days, and most children fully recovered within 10 days.
Notably, we found that those taking five doses of Echinacea daily experienced a shorter average duration of symptoms, cutting the episode time by about 1.7 days compared to those taking three doses. This effective symptom relief led to low antibiotic prescriptions, with only 4.6% of children needing them. Overall, we see Echinacea tablets as a promising option for managing acute cold episodes in children, especially at higher doses.
4
We investigated the effectiveness of echinacea preparations in preventing and treating the common cold. Our exploration included 24 double-blind trials with nearly 4,700 participants, comparing different echinacea products to placebo treatments.
The trials varied in quality, with some showing low risk of bias while others had high risk. Unfortunately, despite our thorough analysis, we found no significant benefits of echinacea for preventing or treating colds. Specifically, trials aimed at prevention did not show a statistical advantage, although there was a slight trend suggesting a possible 10% to 20% risk reduction.
In terms of treatment, only one of the seven trials showed echinacea having any effect on the duration of colds. Additionally, the number of participants leaving the studies due to adverse effects was similar between echinacea and placebo groups. Overall, we conclude that echinacea products haven’t convincingly demonstrated effectiveness for cold relief, even if there are faint hints of potential benefit.
The trials varied in quality, with some showing low risk of bias while others had high risk. Unfortunately, despite our thorough analysis, we found no significant benefits of echinacea for preventing or treating colds. Specifically, trials aimed at prevention did not show a statistical advantage, although there was a slight trend suggesting a possible 10% to 20% risk reduction.
In terms of treatment, only one of the seven trials showed echinacea having any effect on the duration of colds. Additionally, the number of participants leaving the studies due to adverse effects was similar between echinacea and placebo groups. Overall, we conclude that echinacea products haven’t convincingly demonstrated effectiveness for cold relief, even if there are faint hints of potential benefit.
References
- Declerck K, Novo CP, Grielens L, Van Camp G, Suter A, et al. Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences. BMC Complement Med Ther. 2021;21:141. 10.1186/s12906-021-03310-5
- Weishaupt R, Bächler A, Feldhaus S, Lang G, Klein P, et al. Safety and Dose-Dependent Effects of for the Treatment of Acute Cold Episodes in Children: A Multicenter, Randomized, Open-Label Clinical Trial. Children (Basel). 2020;7. 10.3390/children7120292
- Wagner L, Cramer H, Klose P, Lauche R, Gass F, et al. Herbal Medicine for Cough: a Systematic Review and Meta-Analysis. Forsch Komplementmed. 2015;22:359. 10.1159/000442111
- Ross SM. Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold. Holist Nurs Pract. 2016;30:54. 10.1097/HNP.0000000000000130
- Barth A, Hovhannisyan A, Jamalyan K, Narimanyan M. Antitussive effect of a fixed combination of Justicia adhatoda, Echinacea purpurea and Eleutherococcus senticosus extracts in patients with acute upper respiratory tract infection: A comparative, randomized, double-blind, placebo-controlled study. Phytomedicine. 2015;22:1195. 10.1016/j.phymed.2015.10.001
- Karsch-Völk M, Barrett B, Linde K. Echinacea for preventing and treating the common cold. JAMA. 2015;313:618. 10.1001/jama.2014.17145
- Karsch-Völk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, et al. Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev. 2014;2014:CD000530. 10.1002/14651858.CD000530.pub3
- Schapowal A. Efficacy and safety of Echinaforce® in respiratory tract infections. Wien Med Wochenschr. 2013;163:102. 10.1007/s10354-012-0166-0
- Jawad M, Schoop R, Suter A, Klein P, Eccles R. Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial. Evid Based Complement Alternat Med. 2012;2012:841315.
- Barrett B, Brown R, Rakel D, Rabago D, Marchand L, et al. Placebo effects and the common cold: a randomized controlled trial. Ann Fam Med. 2011;9:312. 10.1370/afm.1250
- Mathes A, Bellanger R. Herbs and other dietary supplements: current regulations and recommendations for use to maintain health in the management of the common cold or other related infectious respiratory illnesses. J Pharm Pract. 2010;23:117. 10.1177/0897190009358711
- Arroll B. Common cold. BMJ Clin Evid. 2011;2011.
- Yakoot M, Salem A. Efficacy and safety of a multiherbal formula with vitamin C and zinc (Immumax) in the management of the common cold. Int J Gen Med. 2011;4:45. 10.2147/IJGM.S16266
- Nahas R, Balla A. Complementary and alternative medicine for prevention and treatment of the common cold. Can Fam Physician. 2011;57:31.
- Bieuvelet S, Seyrig C, Leclerc C. [A preliminary survey on the interest of eating probiotics, cypress and echinacea to prevent the apparition of winter infections]. Phytotherapie (Paris). 2011;9:120. 10.1007/s10298-011-0613-x
- Barrett B, Brown R, Rakel D, Mundt M, Bone K, et al. Echinacea for treating the common cold: a randomized trial. Ann Intern Med. 2010;153:769. 10.7326/0003-4819-153-12-201012210-00003
- Puchalski K, Gerstel JA, Jimoh A, Shokoohinia Y, Langland J. Effects of and Alkylamides on Respiratory Virus Replication and IL-8 Expression In Vitro. Molecules. 2025;30. 10.3390/molecules30020386
- Gertsch J, Schoop R, Kuenzle U, Suter A. Echinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways. FEBS Lett. 2004;577:563.
